Dexmedetomidine is a drug that has recently started to be used which has sedative, analgesic and anxiolitic properties. It used in Intensive Care Units for patients with assisted mechanical ventilation, for some types of conscious sedations (the patient can open their eyes, respond to simple commands and cooperate with the nursing staff) and as a contributor to some procedures that require total intravenous anaesthesia (TIVA) as it reduces the need to use inhaled anaesthetics, sedatives and analgesics.  It also has anxiolytic and sympatholytic effects, it provides neurovegetative protection and its cardiovascular and respiratory effects are dose-dependent, which makes them more predictable.

Due to demedetomidine’s sedative capacity which does not provoke respiratory depression, and its moderate analgesic effect, it is also used post-op for many patients.  

Dr. J. B. Dyck is a recognised anaesthesiologist and researcher that has directed or collaborated on different clinical studies about dexmedetomidine, as well as having a large presence within medical literature.  The pharmacokinetic model that carries his name, designed for the use of demedetomidine for target-controlled infusion (TCI), aims to guarantee an appropriate tissue concentration of the drug, whilst taking the patient’s physical characteristics into account.

The Dyck Model for dexmedetomidine in arcomed Chroma pumps

The Dyck model is especially useful for neuroanesthesia, as in many cases it requires that the patient is conscious to some extent during neurosurgical operations because they must be able to respond to stimuli or obey commands from the neurosurgeon. The arcomed Chroma infusion pumps are the only ones on the market that include this pharmacokinetic model, as well as many other models for different drugs (propofol, fentanyl, remifentanyl, midazolam, etc…) for TCI and total intravenous anaesthesia (TIVA) applications.

At arcomed we are always at the forefront of the different applications of intravenous drug infusion, continuously incorporating improvements that, like the Dyck model, facilitate the work of the medical professionals and provide more safety and comfort for the patient.

Welcome to the future of infusions, which with arcomed is already very present.